8DE7

Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM detergent

Summary for 8DE7

• Entry DOI: 10.2210/pdb8de7/pdb
• EMDB information: 27386
• Descriptor: Potassium channel, subfamily K, member 2a, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION (3 entities in total)
• Functional Keywords: ion channel, k2p, k2p2.1, trek1, trek-1, phospholipid, membrane protein
• Biological source: Danio rerio (zebrafish)
• Total number of polymer chains: 2
• Total formula weight: 71746.68

Authors

Schmidpeter, P.A.M.,Nimigean, C.M.,Riegelhaupt, P.M. (deposition date: 2022-06-20, release date: 2023-03-08)

• Primary citation: Schmidpeter, P.A.M.,Petroff 2nd, J.T.,Khajoueinejad, L.,Wague, A.,Frankfater, C.,Cheng, W.W.L.,Nimigean, C.M.,Riegelhaupt, P.M.; Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.; Nat Commun, 14:1077-1077, 2023; PubMed: 36841877; DOI: 10.1038/s41467-023-36765-w

Experimental method

ELECTRON MICROSCOPY (3.27 Å)