8D4V

Crystal Structure of Cathepsin G Inhibited by Eap2 from S. aureus

Summary for 8D4V

Entry DOI	10.2210/pdb8d4v/pdb
Related	84DU 8D4Q 8D4S
Descriptor	Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, SULFATE ION, ... (4 entities in total)
Functional Keywords	protease inhibitor, immune evasion, neutrophil, s. aureus, protein binding, hydrolase-inhibitor, protein binding complex, hydrolase/inhibitor
Biological source	Staphylococcus aureus subsp. aureus Mu50 More
Total number of polymer chains	4
Total formula weight	73033.22
Authors	Gido, C.D.,Herdendorf, T.J.,Geisbrecht, B.V. (deposition date: 2022-06-02, release date: 2022-12-21, Last modification date: 2023-10-25)
Primary citation	Gido, C.D.,Herdendorf, T.J.,Geisbrecht, B.V. Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299:102969-102969, 2023 Cited by PubMed: 36736422 DOI: 10.1016/j.jbc.2023.102969 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation