8D1S
Crystal structure of Plasmodium falciparum GRP78 in complex with Toyocamycin
Summary for 8D1S
Entry DOI | 10.2210/pdb8d1s/pdb |
Descriptor | Chaperone DnaK, 4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, SULFATE ION, ... (4 entities in total) |
Functional Keywords | atpase, chaperone |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 1 |
Total formula weight | 44843.77 |
Authors | Mrozek, A.,Chen, Y.,Antoshchenko, T.,Park, H.W. (deposition date: 2022-05-27, release date: 2023-05-31, Last modification date: 2023-12-13) |
Primary citation | Mrozek, A.,Antoshchenko, T.,Chen, Y.,Zepeda-Velazquez, C.,Smil, D.,Kumar, N.,Lu, H.,Park, H.W. A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues. Front Mol Biosci, 9:956095-956095, 2022 Cited by PubMed: 36275624DOI: 10.3389/fmolb.2022.956095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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