8D1F
hBest2 5mM Ca2+ (Ca2+-bound) closed state
Summary for 8D1F
Entry DOI | 10.2210/pdb8d1f/pdb |
EMDB information | 27127 27128 27129 27130 27131 27132 27133 27134 27135 27136 27137 |
Descriptor | Bestrophin-2, CALCIUM ION, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ... (6 entities in total) |
Functional Keywords | ion channel, chloride channel, anion channel, pentamer, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 5 |
Total formula weight | 270700.74 |
Authors | Owji, A.P.,Kittredge, A.,Hendrickson, W.A.,Tingting, Y. (deposition date: 2022-05-27, release date: 2022-07-13, Last modification date: 2024-02-14) |
Primary citation | Owji, A.P.,Wang, J.,Kittredge, A.,Clark, Z.,Zhang, Y.,Hendrickson, W.A.,Yang, T. Structures and gating mechanisms of human bestrophin anion channels. Nat Commun, 13:3836-3836, 2022 Cited by PubMed: 35789156DOI: 10.1038/s41467-022-31437-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (1.82 Å) |
Structure validation
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