8CR6

mouse Interleukin-12

Summary for 8CR6

• Entry DOI: 10.2210/pdb8cr6/pdb
• Related: 8C7M 8CR5
• Descriptor: Interleukin-12 subunit beta, Interleukin-12 subunit alpha, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: cytokine, inflammation, immunity, heterodimer
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 67493.65

Authors

Merceron, R.,Felix, J.,Lambert, E.,Bloch, Y.,Savvides, S.N. (deposition date: 2023-03-07, release date: 2024-02-07)

• Primary citation: Bloch, Y.,Felix, J.,Merceron, R.,Provost, M.,Symakani, R.A.,De Backer, R.,Lambert, E.,Mehdipour, A.R.,Savvides, S.N.; Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.; Nat.Struct.Mol.Biol., 2024; PubMed: 38287195; DOI: 10.1038/s41594-023-01190-6

Experimental method

X-RAY DIFFRACTION (2.85 Å)