8CBN
structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome
Summary for 8CBN
| Entry DOI | 10.2210/pdb8cbn/pdb |
| EMDB information | 10069 16546 |
| Descriptor | Histone H4, Histone H2A, Histone H2B 1.1, ... (7 entities in total) |
| Functional Keywords | nucleosome, transcription activator, methylation, complex, dna binding protein, transcription |
| Biological source | Xenopus laevis (African clawed frog) More |
| Total number of polymer chains | 12 |
| Total formula weight | 330515.24 |
| Authors | Koutna, E.,Kouba, T.,Novacek, J.,Veverka, V. (deposition date: 2023-01-25, release date: 2023-12-27) |
| Primary citation | Koutna, E.,Lux, V.,Kouba, T.,Skerlova, J.,Novacek, J.,Srb, P.,Hexnerova, R.,Svachova, H.,Kukacka, Z.,Novak, P.,Fabry, M.,Poepsel, S.,Veverka, V. Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51:10011-10025, 2023 Cited by PubMed: 37615563DOI: 10.1093/nar/gkad674 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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