8C67

Crystal structure of Ab25 Fab

Summary for 8C67

Entry DOI	10.2210/pdb8c67/pdb
Descriptor	antibody 25 heavy chain, antibody 25 light chain (3 entities in total)
Functional Keywords	antibody, fab-domain, igg, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	192555.08
Authors	Nyblom, M.,Izadi, A.,Tang, D.,Bahnan, W.,Happonen, L.,Malmstroem, J.,Shannon, O.,Malmstroem, L.,Nordenfelt, P. (deposition date: 2023-01-11, release date: 2024-04-24)
Primary citation	Izadi, A.,Karami, Y.,Bratanis, E.,Wrighton, S.,Khakzad, H.,Nyblom, M.,Olofsson, B.,Happonen, L.,Tang, D.,Nilges, M.,Malmstroem, J.,Bahnan, W.,Shannon, O.,Malmstroem, L.,Nordenfelt, P. Engineering of IgG1 hinge to the flexible IgG3 hinge enhances immune defense against streptococci To Be Published,
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation