8BVT

Cryo-EM structure of rat SLC22A6 bound to probenecid

Summary for 8BVT

• Entry DOI: 10.2210/pdb8bvt/pdb
• EMDB information: 16271
• Descriptor: Solute carrier family 22 member 6, Synthetic nanobody (Sybody), 4-(dipropylsulfamoyl)benzoic acid (3 entities in total)
• Functional Keywords: membrane protein, transporter
• Biological source: Rattus norvegicus (Christmas Island rat); More
• Total number of polymer chains: 2
• Total formula weight: 76918.74

Authors

Parker, J.L.,Kato, T.,Newstead, S. (deposition date: 2022-12-06, release date: 2023-07-19, Last modification date: 2023-11-22)

• Primary citation: Parker, J.L.,Kato, T.,Kuteyi, G.,Sitsel, O.,Newstead, S.; Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.; Nat.Struct.Mol.Biol., 30:1786-1793, 2023; PubMed: 37482561; DOI: 10.1038/s41594-023-01039-y

Experimental method

ELECTRON MICROSCOPY (3.94 Å)