8BGD

Structure of Mpro from SARS-CoV-2 in complex with FGA147

Summary for 8BGD

• Entry DOI: 10.2210/pdb8bgd/pdb
• Descriptor: 3C-like proteinase nsp5, (phenylmethyl) ~{N}-[(2~{S})-4-methyl-1-[[(2~{S})-4-nitro-1-[(3~{R})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-pentan-2-yl]carbamate (3 entities in total)
• Functional Keywords: mpro, sars-cov-2, fga147, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34274.06

Authors

Medrano, F.J.,Romero, A. (deposition date: 2022-10-27, release date: 2023-11-08)

• Primary citation: Medrano, F.J.,Romero, A.; Peptidyl Nitroalkenes Inhibit SARS-CoV-2 Main Protease and Block Virus Replication; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.621 Å)