8B4A

Nativ complex of PqsE and RhlR with autoinducer C4-HSL

Summary for 8B4A

• Entry DOI: 10.2210/pdb8b4a/pdb
• Related: 7R3E 7R3J
• Descriptor: 2-aminobenzoylacetyl-CoA thioesterase, Regulatory protein RhlR, FE (III) ION, ... (5 entities in total)
• Functional Keywords: quorum sensing, luxr-type transcriptional regulator, pseudomonas, dna binding protein, gene regulation, c4-hsl, rhamnolipid, pqs, transcription, signaling protein
• Biological source: Pseudomonas aeruginosa PAO1; More
• Total number of polymer chains: 4
• Total formula weight: 128646.05

Authors

Borgert, S.R.,Blankenfeldt, W. (deposition date: 2022-09-20, release date: 2022-12-14)

• Primary citation: Borgert, S.R.,Henke, S.,Witzgall, F.,Schmelz, S.,Zur Lage, S.,Hotop, S.K.,Stephen, S.,Lubken, D.,Kruger, J.,Gomez, N.O.,van Ham, M.,Jansch, L.,Kalesse, M.,Pich, A.,Bronstrup, M.,Haussler, S.,Blankenfeldt, W.; Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.; Nat Commun, 13:7402-7402, 2022; PubMed: 36456567; DOI: 10.1038/s41467-022-35030-w

Experimental method

X-RAY DIFFRACTION (3.06 Å)