8AZ8

SARS-CoV-2 non-structural protein-1 (nsp1) in complex with 2-(benzylamino)ethan-1-ol

Summary for 8AZ8

• Entry DOI: 10.2210/pdb8az8/pdb
• Related: 8A55
• Descriptor: Host translation inhibitor nsp1, 2-[(phenylmethyl)amino]ethanol (3 entities in total)
• Functional Keywords: sars-cov-2, non-structural protein-1, fragment hit, complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 13260.36

Authors

Ma, S.,Damfo, S.,Pinotsis, N.,Bowler, M.W.,Kozielski, F. (deposition date: 2022-09-05, release date: 2022-11-23, Last modification date: 2024-01-31)

• Primary citation: Ma, S.,Damfo, S.,Lou, J.,Pinotsis, N.,Bowler, M.W.,Haider, S.,Kozielski, F.; Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening.; Int J Mol Sci, 23:-, 2022; PubMed: 36293303; DOI: 10.3390/ijms232012448

Experimental method

X-RAY DIFFRACTION (1.18 Å)