8AYS

SARS-CoV-2 non-structural protein-1 (nsp1) in complex with 4-(2-aminothiazol-4-yl)phenol

Summary for 8AYS

• Entry DOI: 10.2210/pdb8ays/pdb
• Related: 8A55
• Descriptor: Host translation inhibitor nsp1, 4-(2-amino-1,3-thiazol-4-yl)phenol (3 entities in total)
• Functional Keywords: sars-cov-2, non-structural protein-1, fragment hit, complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 13170.20

Authors

Ma, S.,Damfo, S.,Pinotsis, N.,Bowler, M.W.,Kozielski, F. (deposition date: 2022-09-03, release date: 2022-11-23, Last modification date: 2024-02-07)

• Primary citation: Ma, S.,Damfo, S.,Lou, J.,Pinotsis, N.,Bowler, M.W.,Haider, S.,Kozielski, F.; Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening.; Int J Mol Sci, 23:-, 2022; PubMed: 36293303; DOI: 10.3390/ijms232012448

Experimental method

X-RAY DIFFRACTION (1.37 Å)