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8AON

Oxidoreductase fragment of human QSOX1 in complex with a Fab fragment of a humanized anti-QSOX1 antibody

This is a non-PDB format compatible entry.
Summary for 8AON
Entry DOI10.2210/pdb8aon/pdb
Related4IJ3 5D96
DescriptorOxidoreductase fragment of human QSOX1, Heavy chain, Light chain, ... (5 entities in total)
Functional Keywordsantibody, humanized, fab, qsox1, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight74361.47
Authors
Khmelnitsky, L.,Fass, D. (deposition date: 2022-08-08, release date: 2023-08-02)
Primary citationTennenhouse, A.,Khmelnitsky, L.,Yeshaya, N.,Noronha, A.,Lindzen, M.,Khalaila, R.,Zaretsky, I.,Fridmann Sirkis, Y.,Galon-Wolfenson, Y.,Abramson, J.,Yarden, Y.,Fass, D.,Fleishman, S.J.
Reliable energy-based antibody humanization and stabilization
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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