8AM8
Cyclohexanone dehydrogenase (CDH) from Alicycliphilus denitrificans K601 complexed with dehydrogenated substrate - W113A mutant
This is a non-PDB format compatible entry.
Summary for 8AM8
| Entry DOI | 10.2210/pdb8am8/pdb |
| Related | 8AM3 8AM6 |
| Descriptor | Fumarate reductase/succinate dehydrogenase flavoprotein domain protein, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... (7 entities in total) |
| Functional Keywords | fad, cyclic ketone, enzyme engineering, rational design, flavoprotein |
| Biological source | Alicycliphilus denitrificans K601 |
| Total number of polymer chains | 2 |
| Total formula weight | 131909.45 |
| Authors | Prior, S.H.,Taylor, E.J. (deposition date: 2022-08-03, release date: 2024-02-14, Last modification date: 2024-04-10) |
| Primary citation | Singh, W.,Brown, N.L.,McCue, H.V.,Marriott, S.R.,Wilson, R.C.,Perry, J.,Turkenburg, J.P.,Dubey, K.D.,Prior, S.H.,Carnell, A.J.,Taylor, E.J.,Black, G.W. Rational design of a cyclohexanone dehydrogenase for enhanced alpha , beta-desaturation and substrate specificity. Chem Sci, 15:4969-4980, 2024 Cited by PubMed: 38550701DOI: 10.1039/d3sc04009g PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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