8AAE
CAII in complex with para-carboran-propylsulfonamid
Summary for 8AAE
| Entry DOI | 10.2210/pdb8aae/pdb |
| Related | 6YZT 8AA6 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, Para-Carborane propyl-sulfonamide, ... (4 entities in total) |
| Functional Keywords | inhibitor, complex, carbonicanhydrase, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29608.77 |
| Authors | Brynda, J.,Rezacova, P. (deposition date: 2022-07-01, release date: 2023-05-10, Last modification date: 2024-02-07) |
| Primary citation | Fanfrlik, J.,Brynda, J.,Kugler, M.,Lepsik, M.,Pospisilova, K.,Holub, J.,Hnyk, D.,Nekvinda, J.,Gruner, B.,Rezacova, P. B-H⋯ pi and C-H⋯ pi interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Phys Chem Chem Phys, 25:1728-1733, 2023 Cited by PubMed: 36594655DOI: 10.1039/d2cp04673c PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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