8A5J

Crystal structure of Human STE20-like kinase 1, MST1 in complex with compound XMU-MP-1

Summary for 8A5J

• Entry DOI: 10.2210/pdb8a5j/pdb
• Descriptor: Serine/threonine-protein kinase 4 37kDa subunit, 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide (3 entities in total)
• Functional Keywords: serine-threonine kinase, autophosphorylation, mst1, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 64860.25

Authors

Nawrotek, A.,Vuillard, L.,Miallau, L. (deposition date: 2022-06-15, release date: 2022-07-13)

• Primary citation: Weber, C.,Vuillard, L.,Delerive, P.,Miallau, L.; Crystal structure of the Kelch domain of human Keap1in complex with ligand S217879; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.123 Å)