7ZVS

Crystal structure of the Schistosoma mansoni VKR2 kinase domain in an active-like state (ADP-bound)

Summary for 7ZVS

Entry DOI	10.2210/pdb7zvs/pdb
Descriptor	Venus kinase receptor 2, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywords	kinase, active-like state, transferase
Biological source	Schistosoma mansoni
Total number of polymer chains	3
Total formula weight	117271.80
Authors	Beis, K.,Mathavan, I. (deposition date: 2022-05-17, release date: 2022-10-12, Last modification date: 2024-01-31)
Primary citation	Mathavan, I.,Liu, L.J.,Robinson, S.W.,El-Sakkary, N.,Elatico, A.J.J.,Gomez, D.,Nellas, R.,Owens, R.J.,Zuercher, W.,Navratilova, I.,Caffrey, C.R.,Beis, K. Identification of Inhibitors of the Schistosoma mansoni VKR2 Kinase Domain. Acs Med.Chem.Lett., 13:1715-1722, 2022 Cited by PubMed: 36385939 DOI: 10.1021/acsmedchemlett.2c00248 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.07 Å)

Structure validation