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7ZPP

Cryo-EM structure of the MVV CSC intasome at 4.5A resolution

Replaces:  5M0Q
Summary for 7ZPP
Entry DOI10.2210/pdb7zpp/pdb
EMDB information14860
DescriptorIntegrase, vDNA, non-transferred strand, vDNA, transferred strand (3 entities in total)
Functional Keywordsintegrase, intasome, mvv, nucleoprotein complex, retrovirus, viral protein
Biological sourceVisna/maedi virus EV1 KV1772
More
Total number of polymer chains20
Total formula weight542445.03
Authors
Ballandras-Colas, A.,Maskell, D.,Pye, V.E.,Locke, J.,Swuec, S.,Kotecha, A.,Costa, A.,Cherepanov, P. (deposition date: 2022-04-28, release date: 2022-05-11, Last modification date: 2022-10-12)
Primary citationBallandras-Colas, A.,Maskell, D.P.,Serrao, E.,Locke, J.,Swuec, P.,Jonsson, S.R.,Kotecha, A.,Cook, N.J.,Pye, V.E.,Taylor, I.A.,Andresdottir, V.,Engelman, A.N.,Costa, A.,Cherepanov, P.
A supramolecular assembly mediates lentiviral DNA integration
Science, 355:93-95, 2017
Cited by
PubMed: 28059770
DOI: 10.1126/science.aah7002
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.5 Å)
Structure validation

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