7ZOR
Crystal structure of anti-Siglec-15 Fab
Summary for 7ZOR
| Entry DOI | 10.2210/pdb7zor/pdb |
| Descriptor | Anti-siglec15 FAB HC, Anti-siglec15 FAB LC (2 entities in total) |
| Functional Keywords | sialic acid, siglec, immune system, cancer |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 96287.23 |
| Authors | Lenza, M.P.,Oyenarte, I.,Jimenez-Barbero, J.,Ereno-Orbea, J. (deposition date: 2022-04-26, release date: 2023-06-28, Last modification date: 2024-02-07) |
| Primary citation | Lenza, M.P.,Egia-Mendikute, L.,Antonana-Vildosola, A.,Soares, C.O.,Coelho, H.,Corzana, F.,Bosch, A.,Manisha, P.,Quintana, J.I.,Oyenarte, I.,Unione, L.,Moure, M.J.,Azkargorta, M.,Atxabal, U.,Sobczak, K.,Elortza, F.,Sutherland, J.D.,Barrio, R.,Marcelo, F.,Jimenez-Barbero, J.,Palazon, A.,Ereno-Orbea, J. Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b. Nat Commun, 14:3496-3496, 2023 Cited by PubMed: 37311743DOI: 10.1038/s41467-023-39119-8 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.933 Å) |
Structure validation
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