7ZL1

PTX3 Pentraxin Domain

Summary for 7ZL1

Entry DOI	10.2210/pdb7zl1/pdb
EMDB information	14774
Descriptor	Pentraxin-related protein PTX3, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	ptx3, long pentraxin 3, immune system, innate immunity
Biological source	Homo sapiens (human)
Total number of polymer chains	8
Total formula weight	336512.98
Authors	Noone, D.P.,Sharp, T.H. (deposition date: 2022-04-13, release date: 2022-08-03, Last modification date: 2022-08-17)
Primary citation	Noone, D.P.,Dijkstra, D.J.,van der Klugt, T.T.,van Veelen, P.A.,de Ru, A.H.,Hensbergen, P.J.,Trouw, L.A.,Sharp, T.H. PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation. Proc.Natl.Acad.Sci.USA, 119:e2208144119-e2208144119, 2022 Cited by PubMed: 35939690 DOI: 10.1073/pnas.2208144119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation