7Z70
Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with fosinoprilat
Summary for 7Z70
| Entry DOI | 10.2210/pdb7z70/pdb |
| Descriptor | Angiotensin-converting enzyme, CHLORIDE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
| Functional Keywords | angiotensin-1 converting enzyme, fosinoprilat, fosinopril, metalloprotease, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 71003.71 |
| Authors | Cozier, G.E.,Acharya, K.R. (deposition date: 2022-03-14, release date: 2022-06-22, Last modification date: 2024-01-31) |
| Primary citation | Cozier, G.E.,Newby, E.C.,Schwager, S.L.U.,Isaac, R.E.,Sturrock, E.D.,Acharya, K.R. Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat. Febs J., 289:6659-6671, 2022 Cited by PubMed: 35653492DOI: 10.1111/febs.16543 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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