7Z2K

Crystal structure of SARS-CoV-2 Main Protease in orthorhombic space group p212121

Summary for 7Z2K

• Entry DOI: 10.2210/pdb7z2k/pdb
• Descriptor: 3C-like proteinase nsp5, MALONATE ION, SODIUM ION, ... (6 entities in total)
• Functional Keywords: main protease, mpro, cystein protease, drug development, drug target, peptide-like inhibitor, sars-cov-2, covid-19, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68183.48

Authors

Reinke, P.Y.A.,Falke, S.,Lieske, J.,Ewert, W.,Loboda, J.,Rahmani Mashhour, A.,Hauser, M.,Karnicar, K.,Usenik, A.,Lindic, N.,Lach, M.,Boehler, H.,Beck, T.,Cox, R.,Chapman, H.N.,Hinrichs, W.,Turk, D.,Guenther, S.,Meents, A. (deposition date: 2022-02-28, release date: 2023-03-22, Last modification date: 2024-02-07)

• Primary citation: Reinke, P.Y.A.,Falke, S.,Lieske, J.,Ewert, W.,Loboda, J.,Rahmani Mashhour, A.,Hauser, M.,Karnicar, K.,Usenik, A.,Lindic, N.,Lach, M.,Boehler, H.,Beck, T.,Cox, R.,Chapman, H.N.,Hinrichs, W.,Turk, D.,Guenther, S.,Meents, A.; Sulfonated Calpeptin is a promising drug candidate against SARS-CoV-2 infections; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)