7YSE

Crystal structure of E. coli heterotetrameric GlyRS in complex with tRNA

Summary for 7YSE

• Entry DOI: 10.2210/pdb7yse/pdb
• Descriptor: Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, RNA (76-MER), ... (6 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, hetertetramer, drug target, protein-trna complex, transferase, transferase-rna complex, transferase/rna
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 6
• Total formula weight: 275554.86

Authors

Han, L.,Ju, Y.,Zhou, H. (deposition date: 2022-08-12, release date: 2023-02-01, Last modification date: 2023-11-29)

• Primary citation: Han, L.,Luo, Z.,Ju, Y.,Chen, B.,Zou, T.,Wang, J.,Xu, J.,Gu, Q.,Yang, X.L.,Schimmel, P.,Zhou, H.; The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements.; Sci Adv, 9:eadf1027-eadf1027, 2023; PubMed: 36753552; DOI: 10.1126/sciadv.adf1027

Experimental method

X-RAY DIFFRACTION (2.907 Å)