7YP1

Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 10E4 (localized refinement)

Summary for 7YP1

Entry DOI	10.2210/pdb7yp1/pdb
EMDB information	33992
Descriptor	EBV gH, EBV gL, 10E4 heavy chain, ... (4 entities in total)
Functional Keywords	ebv, cryo-em, glycoprotein, ghgl-gp42 complex, antibody, viral protein
Biological source	Human gammaherpesvirus 4 More
Total number of polymer chains	4
Total formula weight	55588.85
Authors	Liu, L.,Sun, H.,Jiang, Y.,Hong, J.,Zheng, Q.,Li, S.,Chen, Y.,Xia, N. (deposition date: 2022-08-02, release date: 2024-01-31)
Primary citation	Hong, J.,Zhong, L.,Liu, L.,Wu, Q.,Zhang, W.,Chen, K.,Wei, D.,Sun, H.,Zhou, X.,Zhang, X.,Kang, Y.F.,Huang, Y.,Chen, J.,Wang, G.,Zhou, Y.,Chen, Y.,Feng, Q.S.,Yu, H.,Li, S.,Zeng, M.S.,Zeng, Y.X.,Xu, M.,Zheng, Q.,Chen, Y.,Zhang, X.,Xia, N. Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4:101296-101296, 2023 Cited by PubMed: 37992686 DOI: 10.1016/j.xcrm.2023.101296 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.54 Å)

Structure validation