7YOY

Cryo-EM structure of EBV gHgL-gp42 in complex with mAbs 3E8 and 5E3 (localized refinement)

Summary for 7YOY

• Entry DOI: 10.2210/pdb7yoy/pdb
• EMDB information: 33990
• Descriptor: Soluble gp42, 5E3 heavy chain, 3E8 heavy chain, ... (5 entities in total)
• Functional Keywords: ebv, cryo-em, glycoprotein, ghgl-gp42 complex, antibody, viral protein
• Biological source: Human gammaherpesvirus 4 (Epstein-Barr virus,HHV-4,Human herpesvirus 4); More
• Total number of polymer chains: 5
• Total formula weight: 64248.65

Authors

Liu, L.,Sun, H.,Jiang, Y.,Hong, J.,Zheng, Q.,Li, S.,Chen, Y.,Xia, N. (deposition date: 2022-08-02, release date: 2024-01-31)

• Primary citation: Hong, J.,Zhong, L.,Liu, L.,Wu, Q.,Zhang, W.,Chen, K.,Wei, D.,Sun, H.,Zhou, X.,Zhang, X.,Kang, Y.F.,Huang, Y.,Chen, J.,Wang, G.,Zhou, Y.,Chen, Y.,Feng, Q.S.,Yu, H.,Li, S.,Zeng, M.S.,Zeng, Y.X.,Xu, M.,Zheng, Q.,Chen, Y.,Zhang, X.,Xia, N.; Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection.; Cell Rep Med, 4:101296-101296, 2023; PubMed: 37992686; DOI: 10.1016/j.xcrm.2023.101296

Experimental method

ELECTRON MICROSCOPY (3.64 Å)