7YDB

Crystal structure of the P450 BM3 heme domain mutant F87V/T268I in complex with N-imidazolyl-pentanoyl-L-phenylalanine,ethylbenzene and hydroxylamine

Summary for 7YDB

• Entry DOI: 10.2210/pdb7ydb/pdb
• Descriptor: Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
• Functional Keywords: p450 bm3 heme domain, oxidoreductase
• Biological source: Priestia megaterium NBRC 15308 = ATCC 14581
• Total number of polymer chains: 2
• Total formula weight: 109190.22

Authors

Dong, S.,Chen, J.,Jiang, Y.,Cong, Z.,Feng, Y. (deposition date: 2022-07-04, release date: 2023-05-24, Last modification date: 2023-11-29)

• Primary citation: Chen, J.,Dong, S.,Fang, W.,Jiang, Y.,Chen, Z.,Qin, X.,Wang, C.,Zhou, H.,Jin, L.,Feng, Y.,Wang, B.,Cong, Z.; Regiodivergent and Enantioselective Hydroxylation of C-H bonds by Synergistic Use of Protein Engineering and Exogenous Dual-Functional Small Molecules.; Angew.Chem.Int.Ed.Engl., 62:e202215088-e202215088, 2023; PubMed: 36417593; DOI: 10.1002/anie.202215088

Experimental method

X-RAY DIFFRACTION (1.472 Å)