7Y8Q
Amyloid-beta assemblage on GM1-containing membranes
Summary for 7Y8Q
Entry DOI | 10.2210/pdb7y8q/pdb |
Descriptor | Amyloid-beta protein 40 (1 entity in total) |
Functional Keywords | amyloid, alzheimer's disease, assemblage, membrane, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 8 |
Total formula weight | 34686.82 |
Authors | Yagi-Utsumi, M.,Itoh, S.G.,Okumura, H.,Yanagisawa, K.,Kato, K.,Nishimura, K. (deposition date: 2022-06-24, release date: 2023-07-05, Last modification date: 2023-09-20) |
Primary citation | Yagi-Utsumi, M.,Itoh, S.G.,Okumura, H.,Yanagisawa, K.,Kato, K.,Nishimura, K. The Double-Layered Structure of Amyloid-beta Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization. Acs Chem Neurosci, 14:2648-2657, 2023 Cited by PubMed: 37482658DOI: 10.1021/acschemneuro.3c00192 PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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