7Y62

Crystal structure of human TFEB HLHLZ domain

Summary for 7Y62

• Entry DOI: 10.2210/pdb7y62/pdb
• Descriptor: Transcription factor EB (2 entities in total)
• Functional Keywords: transcription factor, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 17932.83

Authors

Yang, G.,Li, P.,Lin, Y.,Liu, Z.,Sun, H.,Zhao, Z.,Fang, P.,Wang, J. (deposition date: 2022-06-18, release date: 2023-03-22, Last modification date: 2023-11-29)

• Primary citation: Lin, Y.,Shi, Q.,Yang, G.,Shi, F.,Zhou, Y.,Wang, T.,Xu, P.,Li, P.,Liu, Z.,Sun, H.,Zhao, Z.,Ding, K.,Wang, Z.,Feng, H.,Yu, B.,Fang, P.,Wang, J.; A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.; Proc.Natl.Acad.Sci.USA, 120:e2213670120-e2213670120, 2023; PubMed: 36749723; DOI: 10.1073/pnas.2213670120

Experimental method

X-RAY DIFFRACTION (2 Å)