7Y46

Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state after addition of ATP

Summary for 7Y46

• Entry DOI: 10.2210/pdb7y46/pdb
• Related: 7Y45
• EMDB information: 33602
• Descriptor: Na, K-ATPase alpha subunit, CHOLESTEROL, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (12 entities in total)
• Functional Keywords: na+, k+-atpase, membrane protein, ion transport, transport protein
• Biological source: Squalus acanthias (spiny dogfish); More
• Total number of polymer chains: 6
• Total formula weight: 330260.56

Authors

Kanai, R.,Cornelius, F.,Vilsen, B.,Toyoshima, C. (deposition date: 2022-06-14, release date: 2022-07-13, Last modification date: 2022-10-19)

• Primary citation: Kanai, R.,Cornelius, F.,Vilsen, B.,Toyoshima, C.; Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.; Febs Lett., 596:2513-2524, 2022; PubMed: 35747985; DOI: 10.1002/1873-3468.14437

Experimental method

ELECTRON MICROSCOPY (7.2 Å)