7Y3A

Crystal structure of TRIM7 bound to 2C

Summary for 7Y3A

Entry DOI	10.2210/pdb7y3a/pdb
Descriptor	E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C (2 entities in total)
Functional Keywords	e3 ligase, cytosolic protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	63758.77
Authors	Dong, C.,Yan, X. (deposition date: 2022-06-10, release date: 2022-08-03, Last modification date: 2023-11-29)
Primary citation	Ru, Y.,Yan, X.,Zhang, B.,Song, L.,Feng, Q.,Ye, C.,Zhou, Z.,Yang, Z.,Li, Y.,Zhang, Z.,Li, Q.,Mi, W.,Dong, C. C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119:e2203218119-e2203218119, 2022 Cited by PubMed: 35867826 DOI: 10.1073/pnas.2203218119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation