7Y1T

Complex of integrin alphaV/beta8 and L-TGF-beta1 at a ratio of 1:2

Summary for 7Y1T

• Entry DOI: 10.2210/pdb7y1t/pdb
• EMDB information: 33572
• Descriptor: Integrin alpha-V, Integrin beta-8, Transforming growth factor beta-1 proprotein, ... (9 entities in total)
• Functional Keywords: signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 169751.20

Authors

Duan, Z.,Zhang, Z. (deposition date: 2022-06-08, release date: 2022-08-31, Last modification date: 2022-09-07)

• Primary citation: Duan, Z.,Lin, X.,Wang, L.,Zhen, Q.,Jiang, Y.,Chen, C.,Yang, J.,Lee, C.H.,Qin, Y.,Li, Y.,Zhao, B.,Wang, J.,Zhang, Z.; Specificity of TGF-beta 1 signal designated by LRRC33 and integrin alpha V beta 8.; Nat Commun, 13:4988-4988, 2022; PubMed: 36008481; DOI: 10.1038/s41467-022-32655-9

Experimental method

ELECTRON MICROSCOPY (3.24 Å)