7XRQ

The Catalytic Core Structure of Cystathionine beta-Synthase from Candida albicans

Summary for 7XRQ

Entry DOI	10.2210/pdb7xrq/pdb
Descriptor	Cystathionine beta-synthase, PHOSPHATE ION (3 entities in total)
Functional Keywords	cystathionine beta-synthase, catalytic core center, lyase
Biological source	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Total number of polymer chains	2
Total formula weight	76629.60
Authors	Lou, H.X.,Yu, H.N.,Chang, W.Q. (deposition date: 2022-05-11, release date: 2023-04-19, Last modification date: 2023-11-29)
Primary citation	Chang, W.,Zhang, M.,Jin, X.,Zhang, H.,Zheng, H.,Zheng, S.,Qiao, Y.,Yu, H.,Sun, B.,Hou, X.,Lou, H. Inhibition of fungal pathogenicity by targeting the H 2 S-synthesizing enzyme cystathionine beta-synthase. Sci Adv, 8:eadd5366-eadd5366, 2022 Cited by PubMed: 36525499 DOI: 10.1126/sciadv.add5366 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.501 Å)

Structure validation