7XNA

Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist CYN 154806

Summary for 7XNA

• Entry DOI: 10.2210/pdb7xna/pdb
• Descriptor: Somatostatin receptor type 2,Endo-1,4-beta-xylanase, CYN 154806 (2 entities in total)
• Functional Keywords: g protein-coupled receptor, somatostatin receptor 2, structural protein, signaling protein, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 66683.96

Authors

Zhao, W.,Han, S.,Qiu, N.,Feng, W.,Lu, M.,Yang, D.,Wang, M.-W.,Wu, B.,Zhao, Q. (deposition date: 2022-04-28, release date: 2022-08-03, Last modification date: 2023-11-29)

• Primary citation: Zhao, W.,Han, S.,Qiu, N.,Feng, W.,Lu, M.,Zhang, W.,Wang, M.,Zhou, Q.,Chen, S.,Xu, W.,Du, J.,Chu, X.,Yi, C.,Dai, A.,Hu, L.,Shen, M.Y.,Sun, Y.,Zhang, Q.,Ma, Y.,Zhong, W.,Yang, D.,Wang, M.W.,Wu, B.,Zhao, Q.; Structural insights into ligand recognition and selectivity of somatostatin receptors.; Cell Res., 32:761-772, 2022; PubMed: 35739238; DOI: 10.1038/s41422-022-00679-x

Experimental method

X-RAY DIFFRACTION (2.65 Å)