7XD0

cryo-EM structure of H2BK34ub nucleosome

Summary for 7XD0

• Entry DOI: 10.2210/pdb7xd0/pdb
• EMDB information: 33131
• Descriptor: Histone H4, Histone H2A, Histone H2B type 1-K, ... (7 entities in total)
• Functional Keywords: h2bk34ub nucleosome, nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 193565.61

Authors

Ai, H.S.,Liu, A.J.,Lou, Z.Y.,Liu, L. (deposition date: 2022-03-26, release date: 2022-04-20, Last modification date: 2022-09-07)

• Primary citation: Ai, H.,Sun, M.,Liu, A.,Sun, Z.,Liu, T.,Cao, L.,Liang, L.,Qu, Q.,Li, Z.,Deng, Z.,Tong, Z.,Chu, G.,Tian, X.,Deng, H.,Zhao, S.,Li, J.B.,Lou, Z.,Liu, L.; H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.; Nat.Chem.Biol., 18:972-980, 2022; PubMed: 35739357; DOI: 10.1038/s41589-022-01067-7

Experimental method

ELECTRON MICROSCOPY (3.48 Å)