7XBD
Cryo-EM structure of human galanin receptor 2
Summary for 7XBD
Entry DOI | 10.2210/pdb7xbd/pdb |
EMDB information | 33103 |
Descriptor | Galanin receptor type 2, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, membrane protein, galanin |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 145743.01 |
Authors | Ishimoto, N.,Kita, S.,Park, S.Y. (deposition date: 2022-03-21, release date: 2022-07-13, Last modification date: 2022-08-10) |
Primary citation | Heo, Y.,Ishimoto, N.,Jeon, Y.E.,Yun, J.H.,Ohki, M.,Anraku, Y.,Sasaki, M.,Kita, S.,Fukuhara, H.,Ikuta, T.,Kawakami, K.,Inoue, A.,Maenaka, K.,Tame, J.R.H.,Lee, W.,Park, S.Y. Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface. Plos Biol., 20:e3001714-e3001714, 2022 Cited by PubMed: 35913979DOI: 10.1371/journal.pbio.3001714 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.11 Å) |
Structure validation
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