7X69

Crystal structure of AtHPPD-Y191053 complex

Summary for 7X69

Entry DOI	10.2210/pdb7x69/pdb
Descriptor	4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(4-phenylbutyl)quinazoline-2,4-dione, ... (4 entities in total)
Functional Keywords	inhibitor, complex, oxidoreductase
Biological source	Arabidopsis thaliana (thale cress)
Total number of polymer chains	1
Total formula weight	46472.18
Authors	Lin, H.-Y.,Dong, J.,Yang, G.-F. (deposition date: 2022-03-06, release date: 2022-06-01, Last modification date: 2023-11-29)
Primary citation	Dong, J.,Dong, J.,Yu, X.H.,Yan, Y.C.,Nan, J.X.,Ye, B.Q.,Yang, W.C.,Lin, H.Y.,Yang, G.F. Discovery of Subnanomolar Inhibitors of 4-Hydroxyphenylpyruvate Dioxygenase via Structure-Based Rational Design. J.Agric.Food Chem., 71:1170-1177, 2023 Cited by PubMed: 36599124 DOI: 10.1021/acs.jafc.2c06727 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.797 Å)

Structure validation