7X2W

Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 8A10 (CVB1-pre-A:8A10)

Summary for 7X2W

Entry DOI	10.2210/pdb7x2w/pdb
EMDB information	32973
Descriptor	8A10 light chain, 8A10 heavy chain, Virion protein 1, ... (6 entities in total)
Functional Keywords	coxsackievirus b1, neutralizing antibody, cryo-em, virus
Biological source	Mus musculus More
Total number of polymer chains	6
Total formula weight	119411.90
Authors	Zheng, Q.,Zhu, R.,Sun, H.,Cheng, T.,Li, S.,Xia, N. (deposition date: 2022-02-26, release date: 2022-09-28, Last modification date: 2022-10-05)
Primary citation	Zheng, Q.,Zhu, R.,Yin, Z.,Xu, L.,Sun, H.,Yu, H.,Wu, Y.,Jiang, Y.,Huang, Q.,Huang, Y.,Zhang, D.,Liu, L.,Yang, H.,He, M.,Zhou, Z.,Jiang, Y.,Chen, Z.,Zhao, H.,Que, Y.,Kong, Z.,Zhou, L.,Li, T.,Zhang, J.,Luo, W.,Gu, Y.,Cheng, T.,Li, S.,Xia, N. Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30:1279-, 2022 Cited by PubMed: 36002016 DOI: 10.1016/j.chom.2022.08.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.24 Å)

Structure validation