7X2T

Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (CVB1-M:8A10)

Summary for 7X2T

Entry DOI	10.2210/pdb7x2t/pdb
EMDB information	32970
Descriptor	8A10 light chain, 8A10 heavy chain, Virion protein 1, ... (7 entities in total)
Functional Keywords	coxsackievirus b1, neutralizing antiboy, cryo-em, virus
Biological source	Mus musculus More
Total number of polymer chains	6
Total formula weight	119668.32
Authors	Zheng, Q.,Zhu, R.,Sun, H.,Cheng, T.,Li, S.,Xia, N. (deposition date: 2022-02-26, release date: 2022-09-28, Last modification date: 2022-10-05)
Primary citation	Zheng, Q.,Zhu, R.,Yin, Z.,Xu, L.,Sun, H.,Yu, H.,Wu, Y.,Jiang, Y.,Huang, Q.,Huang, Y.,Zhang, D.,Liu, L.,Yang, H.,He, M.,Zhou, Z.,Jiang, Y.,Chen, Z.,Zhao, H.,Que, Y.,Kong, Z.,Zhou, L.,Li, T.,Zhang, J.,Luo, W.,Gu, Y.,Cheng, T.,Li, S.,Xia, N. Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30:1279-, 2022 Cited by PubMed: 36002016 DOI: 10.1016/j.chom.2022.08.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.69 Å)

Structure validation