7WXZ

Crystal structure of the recombinant protein HR121 from the S2 protein of SARS-CoV-2

Summary for 7WXZ

Entry DOI	10.2210/pdb7wxz/pdb
Descriptor	Spike protein S2' (2 entities in total)
Functional Keywords	sars-cov-2, s2, recombinant protein, hr121, fusion intermediate, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2) More
Total number of polymer chains	4
Total formula weight	88826.71
Authors	Zheng, Y.T.,Ouyang, S.,Pang, W.,Lu, Y.,Zhao, Y.B. (deposition date: 2022-02-15, release date: 2022-11-23, Last modification date: 2023-11-29)
Primary citation	Pang, W.,Lu, Y.,Zhao, Y.B.,Shen, F.,Fan, C.F.,Wang, Q.,He, W.Q.,He, X.Y.,Li, Z.K.,Chen, T.T.,Yang, C.X.,Li, Y.Z.,Xiao, S.X.,Zhao, Z.J.,Huang, X.S.,Luo, R.H.,Yang, L.M.,Zhang, M.,Dong, X.Q.,Li, M.H.,Feng, X.L.,Zhou, Q.C.,Qu, W.,Jiang, S.,Ouyang, S.,Zheng, Y.T. A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein. Cell Res., 32:1068-1085, 2022 Cited by PubMed: 36357786 DOI: 10.1038/s41422-022-00746-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.41 Å)

Structure validation