7WV9
Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein
Summary for 7WV9
Entry DOI | 10.2210/pdb7wv9/pdb |
EMDB information | 32850 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | complex, agonist, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 170389.00 |
Authors | |
Primary citation | Yang, X.,Wang, X.,Xu, Z.,Wu, C.,Zhou, Y.,Wang, Y.,Lin, G.,Li, K.,Wu, M.,Xia, A.,Liu, J.,Cheng, L.,Zou, J.,Yan, W.,Shao, Z.,Yang, S. Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18:831-840, 2022 Cited by PubMed: 35637350DOI: 10.1038/s41589-022-01038-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.36 Å) |
Structure validation
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