7WNN

Crystal structure of Imine Reductase from Actinoalloteichus hymeniacidonis in complex with NADPH

Summary for 7WNN

Entry DOI	10.2210/pdb7wnn/pdb
Descriptor	3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	imine reductase, nadph, ired, oxidoreductase
Biological source	Actinoalloteichus hymeniacidonis
Total number of polymer chains	2
Total formula weight	71913.89
Authors	Zhang, J.,Chen, R.,Gao, S. (deposition date: 2022-01-19, release date: 2022-04-06, Last modification date: 2022-06-08)
Primary citation	Zhang, J.,Liao, D.,Chen, R.,Zhu, F.,Ma, Y.,Gao, L.,Qu, G.,Cui, C.,Sun, Z.,Lei, X.,Gao, S.S. Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering. Angew.Chem.Int.Ed.Engl., 61:e202201908-e202201908, 2022 Cited by PubMed: 35322515 DOI: 10.1002/anie.202201908 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation