7WFY
Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide
Summary for 7WFY
| Entry DOI | 10.2210/pdb7wfy/pdb |
| Descriptor | Guanine nucleotide exchange factor VAV2, Amyloid beta A4 protein-binding family B member 1 (protein) (3 entities in total) |
| Functional Keywords | complex, protein binding |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 14895.55 |
| Authors | Zhang, Y.J.,Liu, Y.R.,Wu, B. (deposition date: 2021-12-27, release date: 2022-12-07, Last modification date: 2023-11-29) |
| Primary citation | Zhang, Y.,Yang, X.,Liu, Y.,Ge, L.,Wang, J.,Sun, X.,Wu, B.,Wang, J. Vav2 is a novel APP-interacting protein that regulates APP protein level. Sci Rep, 12:12752-12752, 2022 Cited by PubMed: 35882892DOI: 10.1038/s41598-022-16883-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.449 Å) |
Structure validation
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