7W6Y

Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P1

Summary for 7W6Y

Entry DOI	10.2210/pdb7w6y/pdb
Descriptor	Anti sigma-E protein, RseA, ZINC ION, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE (3 entities in total)
Functional Keywords	intramembrane protease, hydrolase
Biological source	Kangiella koreensis DSM 16069
Total number of polymer chains	1
Total formula weight	50986.32
Authors	Imaizumi, Y.,Takanuki, K.,Nogi, T. (deposition date: 2021-12-02, release date: 2022-09-07)
Primary citation	Imaizumi, Y.,Takanuki, K.,Miyake, T.,Takemoto, M.,Hirata, K.,Hirose, M.,Oi, R.,Kobayashi, T.,Miyoshi, K.,Aruga, R.,Yokoyama, T.,Katagiri, S.,Matsuura, H.,Iwasaki, K.,Kato, T.,Kaneko, M.K.,Kato, Y.,Tajiri, M.,Akashi, S.,Nureki, O.,Hizukuri, Y.,Akiyama, Y.,Nogi, T. Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci Adv, 8:eabp9011-eabp9011, 2022 Cited by PubMed: 36001659 DOI: 10.1126/sciadv.abp9011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation