7W1W

NADPH-bound AKR4C17 mutant F291D

Summary for 7W1W

• Entry DOI: 10.2210/pdb7w1w/pdb
• Descriptor: AKR4-2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: glyphosate resistance, gpj degradation mechanism, aldo-keto reductase, structure-based engineering, oxidoreductase
• Biological source: Echinochloa colona
• Total number of polymer chains: 2
• Total formula weight: 72114.88

Authors

Li, H.,Yang, Y.,Hu, Y.,Chen, C.-C.,Huang, J.-W.,Min, J.,Dai, L.,Guo, R.-T. (deposition date: 2021-11-21, release date: 2022-07-06, Last modification date: 2023-11-29)

• Primary citation: Li, H.,Yang, Y.,Hu, Y.,Chen, C.C.,Huang, J.W.,Min, J.,Dai, L.,Guo, R.T.; Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona; J Hazard Mater, 436:129191-, 2022; DOI: 10.1016/j.jhazmat.2022.129191

Experimental method

X-RAY DIFFRACTION (1.82 Å)