7W1S

Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-007

Summary for 7W1S

• Entry DOI: 10.2210/pdb7w1s/pdb
• Descriptor: Spike protein S1, Nanobody Nb-007 (3 entities in total)
• Functional Keywords: viral protein/immune system, viral protein-immune system complex
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 2
• Total formula weight: 37621.24

Authors

Yang, J.,Lin, S.,Sun, H.L.,Lu, G.W. (deposition date: 2021-11-20, release date: 2022-06-29, Last modification date: 2023-11-29)

• Primary citation: Yang, J.,Lin, S.,Sun, H.,Chen, Z.,Yang, F.,Lin, X.,Guo, L.,Wang, L.,Wen, A.,Zhang, X.,Dai, Y.,He, B.,Cao, Y.,Dong, H.,Liu, X.,Chen, B.,Li, J.,Zhao, Q.,Lu, G.; A Potent Neutralizing Nanobody Targeting the Spike Receptor-Binding Domain of SARS-CoV-2 and the Structural Basis of Its Intimate Binding.; Front Immunol, 13:820336-820336, 2022; PubMed: 35663966; DOI: 10.3389/fimmu.2022.820336

Experimental method

X-RAY DIFFRACTION (1.997 Å)