7V93

Cryo-EM structure of the Cas12c2-sgRNA binary complex

This is a non-PDB format compatible entry.

Summary for 7V93

• Entry DOI: 10.2210/pdb7v93/pdb
• EMDB information: 31807 31808
• Descriptor: cas12c2, sgRNA (2 entities in total)
• Functional Keywords: cas12c, c2c3, sgrna, crispr, rna binding protein-rna complex, rna binding protein/rna
• Biological source: uncultured archaeon; More
• Total number of polymer chains: 2
• Total formula weight: 174496.35

Authors

Kurihara, N.,Hirano, H.,Tomita, A.,Kobayashi, K.,Kusakizako, T.,Nishizawa, T.,Yamashita, K.,Nishimasu, H.,Nureki, O. (deposition date: 2021-08-24, release date: 2022-04-13, Last modification date: 2022-06-01)

• Primary citation: Kurihara, N.,Nakagawa, R.,Hirano, H.,Okazaki, S.,Tomita, A.,Kobayashi, K.,Kusakizako, T.,Nishizawa, T.,Yamashita, K.,Scott, D.A.,Nishimasu, H.,Nureki, O.; Structure of the type V-C CRISPR-Cas effector enzyme.; Mol.Cell, 82:1865-1877.e4, 2022; PubMed: 35366394; DOI: 10.1016/j.molcel.2022.03.006

Experimental method

ELECTRON MICROSCOPY (2.9 Å)