7UX0

Human Sperm TMEM95 Ectodomain

Summary for 7UX0

Entry DOI	10.2210/pdb7ux0/pdb
Descriptor	Sperm-egg fusion protein TMEM95, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	fertilization, sperm-egg binding, sperm-egg fusion, acrosomal membrane protein, cell adhesion
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	14687.88
Authors	Tang, S.,Kim, P.S. (deposition date: 2022-05-04, release date: 2022-10-12)
Primary citation	Tang, S.,Lu, Y.,Skinner, W.M.,Sanyal, M.,Lishko, P.V.,Ikawa, M.,Kim, P.S. Human sperm TMEM95 binds eggs and facilitates membrane fusion. Proc.Natl.Acad.Sci.USA, 119:e2207805119-e2207805119, 2022 Cited by PubMed: 36161911 DOI: 10.1073/pnas.2207805119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.49 Å)

Structure validation