7UWO

Structure of beta-catenin in complex with FP05874, a Helicon Polypeptide

Summary for 7UWO

• Entry DOI: 10.2210/pdb7uwo/pdb
• Related: 7UWI
• Descriptor: Catenin beta-1, Helicon Polypeptide FP05874, N,N'-(1,4-phenylene)diacetamide, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, stapled, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 60178.69

Authors

Agarwal, S.,Thomson, T.,Wahl, S.,Ramirez, J.,Hriniak, B.,Verdine, G.,McGee, J. (deposition date: 2022-05-03, release date: 2022-12-28, Last modification date: 2023-10-25)

• Primary citation: Li, K.,Tokareva, O.S.,Thomson, T.M.,Wahl, S.C.T.,Travaline, T.L.,Ramirez, J.D.,Choudary, S.K.,Agarwal, S.,Walkup 4th, W.G.,Olsen, T.J.,Brennan, M.J.,Verdine, G.L.,McGee, J.H.; De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.; Proc.Natl.Acad.Sci.USA, 119:e2210435119-e2210435119, 2022; PubMed: 36534810; DOI: 10.1073/pnas.2210435119

Experimental method

X-RAY DIFFRACTION (2.75 Å)