7USS

Plasmodium falciparum protein Pfs230 Pro-D1D2 - Structure of the first two 6-cysteine domains with N-terminal extension

Summary for 7USS

• Entry DOI: 10.2210/pdb7uss/pdb
• Descriptor: Gametocyte surface protein P230, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, ... (5 entities in total)
• Functional Keywords: 6-cysteine protein, s48/45 domain, plasmodium, cell adhesion
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 2
• Total formula weight: 83481.31

Authors

Dietrich, M.H.,Tham, W.H. (deposition date: 2022-04-25, release date: 2022-12-28, Last modification date: 2023-10-25)

• Primary citation: Dietrich, M.H.,Gabriela, M.,Reaksudsan, K.,Dixon, M.W.A.,Chan, L.J.,Adair, A.,Trickey, S.,O'Neill, M.T.,Tan, L.L.,Lopaticki, S.,Healer, J.,Keremane, S.,Cowman, A.F.,Tham, W.H.; Nanobodies against Pfs230 block Plasmodium falciparum transmission.; Biochem.J., 479:2529-2546, 2022; PubMed: 36520108; DOI: 10.1042/BCJ20220554

Experimental method

X-RAY DIFFRACTION (1.9 Å)