7UR4

Cryo-EM Structure of the Neutralizing Antibody MPV467 in Complex with Prefusion Human Metapneumovirus F Glycoprotein

Summary for 7UR4

Entry DOI	10.2210/pdb7ur4/pdb
EMDB information	26704
Descriptor	Fusion glycoprotein F0, MPV467 Fab Heavy chain, MPV467 Fab Light chain, ... (5 entities in total)
Functional Keywords	neutralizing antibody, fusion protein, metapneumovirus, viral protein-immune system complex, viral protein/immune system
Biological source	Human metapneumovirus More
Total number of polymer chains	9
Total formula weight	324493.77
Authors	Rush, S.A.,McLellan, J.S. (deposition date: 2022-04-21, release date: 2022-06-08, Last modification date: 2022-06-29)
Primary citation	Banerjee, A.,Huang, J.,Rush, S.A.,Murray, J.,Gingerich, A.D.,Royer, F.,Hsieh, C.L.,Tripp, R.A.,McLellan, J.S.,Mousa, J.J. Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus. Proc.Natl.Acad.Sci.USA, 119:e2203326119-e2203326119, 2022 Cited by PubMed: 35696580 DOI: 10.1073/pnas.2203326119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.34 Å)

Structure validation